Born: New Delhi
Ph.D.: Delhi University (2005)
Post Doctoral Fellow: University of Rhode Island, USA (2005-2008)
Amity University U.P.: July 2008-Nov 2010
Indian Institute of Technology Delhi: Dec 2010-present
Catalysis by ionic liquid stabilized transition metal nanoparticles: Nanoparticle catalysts have gained importance as they are efficient, recyclable, and meet the modern requirements for green catalysts. Since they exhibit a high surface to bulk metal ratio, large enhancements in the activity and selectivity are seen when they are used as catalysts. Ionic liquids play a key role here, as they tend to stabilize these nanoparticles showing a positive effect on the reaction rates. Our objective is to develop efficient and reusable nanocatalytic systems essentially based on palladium and copper, stabilized by task-specific ionic liquids, and use them for cross-coupling reactions under mild conditions.
Palladium and copper assisted selective C-H functionalization: The concept of chelation assistance by directing groups in catalytic functionalization of C-H bonds has emerged as a powerful tool in organic synthesis. We are focused towards atom economic conversion of C-H bonds into carbon-carbon and carbon-heteroatom bonds using palladium and copper based catalytic systems.
Development of new synthetic methods, strategies, and concepts in organic synthesis.
C. Premi, A. Dixit and N. Jain, Palladium catalyzed regioselective decarboxylative alkylation of arenes and heteroarenes with aliphatic carboxylic acids, Org. Lett., 2015, 17, 2598-2601.
P. Sharma, S. Rohilla and N. Jain, Copper acetate-DMSO promoted methylthiolation of arenes and heteroarenes, J. Org. Chem., 2015, 80, 4116-4122.
A. Srivastava, L. Aggarwal and N. Jain, One-pot sequential alkylation and cycloaddition: Regioselective construction and biological evaluation of novel benzoxazole-triazole derivatives, ACS Combinatorial Science, 2015, 17, 39-48.
A. K. Jha, S. Kishor and N. Jain, Aryl alkyl carbene-Pd complex assisted C-Cl bond activation: An unprecedented cross-coupling route to trans-stilbenes, RSC Adv., 2015, 5, 55218-55226.